John Detre, MD

University of Pennsylvania

John Detre’s research expertise is functional Neuroimaging. His research focuses on cerebral blood flow and metabolism under normal conditions and in response to brain injury. Specific conditions under investigation include functional activation of human brain in response to cognitive and sensorimotor tasks, epilepsy, cerebrovascular disease, and strokes. This research primarily utilizes magnetic resonance techniques including functional imaging techniques and spectroscopy, often correlated with other methods. Dr. Detre is widely known for seminal work in the development of a noninvasive quantitative perfusion method utilizing arterial spin labeled (ASL) blood water as a diffusible tracer for flow quantification. He directs the Center for Functional Neuroimaging.