Calum MacRae, MD, PhD

Harvard University
Zebrafish Models

Dr. MacRae's group has developed physiologic assays in zebrafish for cardiovascular traits, as well as reporters for disease pathways and for a range of drug toxicities. Automating and scaling these assays for high-throughput has enabled 'omic scale in vivo physiology and pharmacology screens in zebrafish disease models. Dr. MacRae's expertise is in genetic screens in disease models to identify novel pathway members and to explore gene-environment interactions, in particular pharmacogenetics.