Publications

2014
Roberts LD, Koulman A, Griffin JL.  2014.  Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome. Lancet Diabetes Endocrinol. 2(1):65-75.
2015
Grevengoed TJ, Martin SA, Katunga L, Cooper DE, Anderson EJ, Murphy RC, Coleman RA.  2015.  Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res. 56(8):1572-82.
Hayer KE, Pizarro A, Lahens NF, Hogenesch JB, Grant GR.  2015.  Benchmark Analysis of Algorithms for Determining and Quantifying Full-length mRNA Splice Forms from RNA-Seq Data. Bioinformatics.
Liang X, Bittinger K, Li X, Abernethy DR, Bushman FD, FitzGerald GA.  2015.  Bidirectional interactions between indomethacin and the murine intestinal microbiota.. Elife. 4
Chatr-Aryamontri A, Breitkreutz B-J, Oughtred R, Boucher L, Heinicke S, Chen D, Stark C, Breitkreutz A, Kolas N, O'Donnell L et al..  2015.  The BioGRID interaction database: 2015 update. Nucleic Acids Res. 43(Database issue):D470-8.
Yuan C, Smith WL.  2015.  A Cyclooxygenase-2-dependent Prostaglandin E2 Biosynthetic System in the Golgi Apparatus. J Biol Chem. 290(9):5606-20.
Griffin JL, Wang X, Stanley E.  2015.  Does our gut microbiome predict cardiovascular risk? A review of the evidence from metabolomics. Circ Cardiovasc Genet. 8(1):187-91.
Proia RL, Hla T.  2015.  Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy. J Clin Invest. 125(4):1379-87.
Li X, Ballantyne LL, Che X, Mewburn JD, Kang JX, Barkley RM, Murphy RC, Yu Y, Funk CD.  2015.  Endogenously generated omega-3 fatty acids attenuate vascular inflammation and neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice. J Am Heart Assoc. 4(4)
Goya J, Wong AK, Yao V, Krishnan A, Homilius M, Troyanskaya OG.  2015.  FNTM: a server for predicting functional networks of tissues in mouse. Nucleic Acids Res. 43(W1):W182-7.
Prilutsky D, Kho AT, Palmer NP, Bhakar AL, Smedemark-Margulies N, Kong SWon, Margulies DM, Bear MF, Kohane IS.  2015.  Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures.. Mol Autism. 6:66.
Xiang Y, Cheng J, Wang D, Hu X, Xie Y, Stitham J, Atteya G, Du J, Tang WHo, Lee SHee et al..  2015.  Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor. Blood. 125(22):3377-87.
Wong AK, Krishnan A, Yao V, Tadych A, Troyanskaya OG.  2015.  IMP 2.0: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks. Nucleic Acids Res. 43(W1):W128-33.
Iyengar R, Altman RB, Troyanskya O, FitzGerald GA.  2015.  MEDICINE. Personalization in practice. Science. 350(6258):282-3.
Castro C, Briggs W, Paschos GK, FitzGerald GA, Griffin JL.  2015.  A metabolomic study of adipose tissue in mice with a disruption of the circadian system. Mol Biosyst. 11(7):1897-906.
Mazaleuskaya LL, Theken KN, Gong L, Thorn CF, FitzGerald GA, Altman RB, Klein TE.  2015.  PharmGKB summary: ibuprofen pathways. Pharmacogenet Genomics. 25(2):96-106.
Mazaleuskaya LL, Sangkuhl K, Thorn CF, FitzGerald GA, Altman RB, Klein TE.  2015.  PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses. Pharmacogenet Genomics. 25(8):416-26.
Altman RB.  2015.  Predicting cancer drug response: advancing the DREAM. Cancer Discov. 5(3):237-8.
Liu T, Altman RB.  2015.  Relating Essential Proteins to Drug Side-Effects Using Canonical Component Analysis: A Structure-Based Approach. J Chem Inf Model. 55(7):1483-94.
Liang X, Bushman FD, FitzGerald GA.  2015.  Rhythmicity of the intestinal microbiota is regulated by gender and the host circadian clock. Proc Natl Acad Sci U S A. 112(33):10479-84.
Greene CS, Krishnan A, Wong AK, Ricciotti E, Zelaya RA, Himmelstein DS, Zhang R, Hartmann BM, Zaslavsky E, Sealfon SC et al..  2015.  Understanding multicellular function and disease with human tissue-specific networks. Nat Genet. 47(6):569-76.
2016
Mazaleuskaya LL, Lawson JA, Li X, Grant G, Mesaros C, Grosser T, Blair IA, Ricciotti E, FitzGerald GA.  2016.  A broad-spectrum lipidomics screen of antiinflammatory drug combinations in human blood. JCI Insight. 1(12)
Dong L, Zou H, Yuan C, Hong YH, Kuklev DV, Smith WL.  2016.  Different Fatty Acids Compete with Arachidonic Acid for Binding to the Allosteric or Catalytic Subunits of Cyclooxygenases to Regulate Prostanoid Synthesis. J Biol Chem. 291(8):4069-78.
Guo L, Worth AJ, Mesaros C, Snyder NW, Glickson JD, Blair IA.  2016.  Diisopropylethylamine/hexafluoroisopropanol-mediated ion-pairing ultra-high-performance liquid chromatography/mass spectrometry for phosphate and carboxylate metabolite analysis: utility for studying cellular metabolism. Rapid Commun Mass Spectrom. 30(16):1835-45.
Stitham J, Hwa J.  2016.  Prostacyclin, Atherothrombosis and Diabetes Mellitus: Physiologic and Clinical Considerations.. Curr Mol Med. 16(4):328-42.

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