Publications
Differential impairment of aspirin-dependent platelet cyclooxygenase acetylation by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A. 111(47):16830-5.
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2014. Rhythmicity of the intestinal microbiota is regulated by gender and the host circadian clock. Proc Natl Acad Sci U S A. 112(33):10479-84.
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2015. .
2015. Ten-eleven translocation-2 (TET2) is a master regulator of smooth muscle cell plasticity. Circulation. 128(18):2047-57.
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2013. Relating Essential Proteins to Drug Side-Effects Using Canonical Component Analysis: A Structure-Based Approach. J Chem Inf Model. 55(7):1483-94.
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2015. ELAVL1 Modulates Transcriptome-wide miRNA Binding in Murine Macrophages. Cell Rep. 9(6):2330-43.
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2014. Measurement of lysophospholipid acyltransferase activities using substrate competition. J Lipid Res. 55(4):782-91.
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2014. PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses. Pharmacogenet Genomics. 25(8):416-26.
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2015. PharmGKB summary: ibuprofen pathways. Pharmacogenet Genomics. 25(2):96-106.
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2015. A broad-spectrum lipidomics screen of antiinflammatory drug combinations in human blood. JCI Insight. 1(12)
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2016. Editorial: pharmacogenetics and molecular medicine: "so close and yet so far". Curr Mol Med. 14(7):803-4.
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2014. Platelet lipidomics: modern day perspective on lipid discovery and characterization in platelets. Circ Res. 114(7):1185-203.
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2014. Individual variation of human S1P1 coding sequence leads to heterogeneity in receptor function and drug interactions. J Lipid Res. 55(12):2665-75.
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2014. Gene expression analysis in Fmr1KO mice identifies an immunological signature in brain tissue and mGluR5-related signaling in primary neuronal cultures.. Mol Autism. 6:66.
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2015. Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy. J Clin Invest. 125(4):1379-87.
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2015. Towards metabolic biomarkers of insulin resistance and type 2 diabetes: progress from the metabolome. Lancet Diabetes Endocrinol. 2(1):65-75.
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2014. .
2016.
Chemotherapeutic agents subvert tumor immunity by generating agonists of platelet-activating factor. Cancer Res. 74(23):7069-78.
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2014. Stable isotope dilution liquid chromatography/mass spectrometry analysis of cellular and tissue medium- and long-chain acyl-coenzyme A thioesters. Rapid Commun Mass Spectrom. 28(16):1840-8.
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2014. Cardiovascular pharmacogenetics of anti-thrombotic agents and non-steroidal anti-inflammatory drugs. Curr Mol Med. 14(7):909-31.
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2014. Prostacyclin, Atherothrombosis and Diabetes Mellitus: Physiologic and Clinical Considerations.. Curr Mol Med. 16(4):328-42.
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2016. Aldose reductase-mediated phosphorylation of p53 leads to mitochondrial dysfunction and damage in diabetic platelets. Circulation. 129(15):1598-609.
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2014. Detection theory in identification of RNA-DNA sequence differences using RNA-sequencing. PLoS One. 9(11):e112040.
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2014. Cardiovascular pharmacogenetics of antihypertensive and lipid- lowering therapies. Curr Mol Med. 14(7):849-79.
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2014. IMP 2.0: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks. Nucleic Acids Res. 43(W1):W128-33.
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2015.