Publications
Relating Essential Proteins to Drug Side-Effects Using Canonical Component Analysis: A Structure-Based Approach. J Chem Inf Model. 55(7):1483-94.
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2015. Rhythmicity of the intestinal microbiota is regulated by gender and the host circadian clock. Proc Natl Acad Sci U S A. 112(33):10479-84.
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2015. Microfluidic assay of platelet deposition on collagen by perfusion of whole blood from healthy individuals taking aspirin. Clin Chem. 59(8):1195-204.
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2013. .
2016. SEPARATING THE CAUSES AND CONSEQUENCES IN DISEASE TRANSCRIPTOME. Pac Symp Biocomput. 21:381-92.
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2016. Endogenously generated omega-3 fatty acids attenuate vascular inflammation and neointimal hyperplasia by interaction with free fatty acid receptor 4 in mice. J Am Heart Assoc. 4(4)
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2015. Differential impairment of aspirin-dependent platelet cyclooxygenase acetylation by nonsteroidal antiinflammatory drugs. Proc Natl Acad Sci U S A. 111(47):16830-5.
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2014. Major urinary metabolites of 6-keto-prostaglandin F2α in mice. J Lipid Res. 54(7):1906-14.
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2013. A form of the metabolic syndrome associated with mutations in DYRK1B. N Engl J Med. 370(20):1909-19.
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2014. Biomarkers for personalizing omega-3 fatty acid dosing. Cancer Prev Res (Phila). 7(10):1011-22.
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2014. MEDICINE. Personalization in practice. Science. 350(6258):282-3.
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2015.
Diisopropylethylamine/hexafluoroisopropanol-mediated ion-pairing ultra-high-performance liquid chromatography/mass spectrometry for phosphate and carboxylate metabolite analysis: utility for studying cellular metabolism. Rapid Commun Mass Spectrom. 30(16):1835-45.
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2016. Does our gut microbiome predict cardiovascular risk? A review of the evidence from metabolomics. Circ Cardiovasc Genet. 8(1):187-91.
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2015. Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res. 56(8):1572-82.
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2015. Understanding multicellular function and disease with human tissue-specific networks. Nat Genet. 47(6):569-76.
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2015. FNTM: a server for predicting functional networks of tissues in mouse. Nucleic Acids Res. 43(W1):W182-7.
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2015. Integrating systems biology sources illuminates drug action. Clin Pharmacol Ther. 95(6):663-9.
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2014. Human thromboxane A2 receptor genetic variants: in silico, in vitro and "in platelet" analysis. PLoS One. 8(6):e67314.
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2013. Historical lessons in translational medicine: cyclooxygenase inhibition and P2Y12 antagonism. Circ Res. 112(1):174-94.
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2013. Different Fatty Acids Compete with Arachidonic Acid for Binding to the Allosteric or Catalytic Subunits of Cyclooxygenases to Regulate Prostanoid Synthesis. J Biol Chem. 291(8):4069-78.
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2016. Pre-existent asymmetry in the human cyclooxygenase-2 sequence homodimer. J Biol Chem. 288(40):28641-55.
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2013. Myeloid Cell COX-2 deletion reduces mammary tumor growth through enhanced cytotoxic T-lymphocyte function. Carcinogenesis. 35(8):1788-97.
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2014. The BioGRID interaction database: 2015 update. Nucleic Acids Res. 43(Database issue):D470-8.
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