Gene Set Gene Set Qualifier Gene Name Alternative Names Recommended Name UniProt ID NCBI Gene ID EC Species Name Taxonomy ID Pathway Information Source Evidence Type PubMed ID Notes Notes/SubPathway BP ACE P12821 1636 Human 9606 Metabolism of angiotensinogen to angiotensins REACT_147707.2 Blood pressure/Vascular tone BP ACE2 Q9BYF1 59272 Human 9606 GO:BP 18258853 BP ACVRL1 P37023 94 Human 9606 GO:BP 14684682 BP ADIPOQ Q15848 9370 Human 9606 GO:BP 17327472 BP ADM P35318 133 Human 9606 GO:BP 11410113 BP AGT P01019 183 Human 9606 Metabolism of angiotensinogen to angiotensins REACT_147707.2 Blood pressure/Vascular tone BP AGTR1 P30556 185 Human 9606 GO:BP 15117835 BP AGTR2 P50052 186 Human 9606 GO:BP 15117835 17159079 BP AKT1 P31749 207 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP ANPEP P15144 290 Human 9606 Metabolism of angiotensinogen to angiotensins REACT_147707.2 Blood pressure/Vascular tone BP ATP6AP2 O75787 10159 Human 9606 GO:BP REACT_147707.2 12045255 15746149 BP BMPR2 Q13873 659 Human 9606 GO:BP 18364108 BP CALCA P06881 796 Human 9606 GO:BP 10642343 3266556 BP CALM1 P62158 801 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP CARTPT Q16568 9607 Human 9606 GO:BP 11711504 BP CAV1 Q03135 857 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP CD34 P28906 947 Human 9606 GO:BP 17505307 BP CMA1 P23946 1215 Human 9606 Metabolism of angiotensinogen to angiotensins REACT_147707.2 Blood pressure/Vascular tone BP COL1A2 P08123 1278 Human 9606 GO:BP 17334644 BP CORIN Q9Y5Q5 10699 Human 9606 GO:BP 22437503 BP CPA3 P15088 1359 Human 9606 Metabolism of angiotensinogen to angiotensins REACT_147707.2 Blood pressure/Vascular tone BP CPS1 P31327 1373 Human 9606 GO:BP 14718356 BP CTSG P08311 1511 Human 9606 Metabolism of angiotensinogen to angiotensins REACT_147707.2 Blood pressure/Vascular tone BP CTSZ Q9UBR2 1522 Human 9606 Metabolism of angiotensinogen to angiotensins REACT_147707.2 Blood pressure/Vascular tone BP CYP11B1 P15538 1584 Human 9606 GO:BP 2022736 BP CYP11B2 P19099 1585 Human 9606 GO:BP 14614232 BP DHFR P00374 1719 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP DNM2 P50570 1785 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP ECE1 P42892 1889 Human 9606 GO:BP 7805846 BP EDN1 P05305 1906 Human 9606 GO:BP 2649896 8982507 9422810 11410113 BP EDN2 P20800 1907 Human 9606 GO:BP 2649896 8982507 9422810 BP EDN3 P14138 1908 Human 9606 GO:BP 2649896 8982507 BP EDNRA P25101 1909 Human 9606 GO:BP 8982507 BP EDNRB P24530 1910 Human 9606 GO:BP 8982507 BP ENG P17813 2022 Human 9606 GO:BP 18974388 BP ENPEP Q07075 2028 Human 9606 GO:BP 19608358 BP GCH1 P30793 2643 Human 9606 GO:BP 17717598 BP GCHFR P30047 2644 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP GCLC P48506 2729 Human 9606 GO:BP 12598062 BP GCLM P48507 2730 Human 9606 GO:BP 12975258 BP HSP90AA1 P07900 3320 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP HTR2B P41595 3357 Human 9606 GO:BP 15625277 BP LRP5 O75197 4041 Human 9606 GO:BP 18721193 BP LYPLA1 O75608 10434 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP MME P08473 4311 Human 9606 Metabolism of angiotensinogen to angiotensins REACT_147707.2 Blood pressure/Vascular tone BP NOS1 P29475 4842 Human 9606 GO:BP 18048451 18391107 BP NOS3 P29474 4846 Human 9606 GO:BP 8999856 BP NOSIP Q9Y314 51070 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP NOSTRIN Q8IVI9 115677 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP NPPA P01160 4878 Human 9606 GO:BP 6230082 6547996 BP P2RX4 Q99571 5025 Human 9606 GO:BP 11606481 15130891 BP PCSK5 Q92824 5125 Human 9606 GO:BP 8901832 BP PLCB3 Q01970 5331 Human 9606 GO:BP 18468998 BP PPARG P37231 5468 Human 9606 GO:BP 10622252 BP PRKG2 Q13237 5593 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP PTS Q03393 5805 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP REN P00797 5972 Human 9606 GO:BP 12045255 BP SPR P35270 6697 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP WASL O00401 8976 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone BP ZDHHC21 Q8IVQ6 340481 Human 9606 eNOS activation and regulation REACT_147707.2 Blood pressure/Vascular tone AAE Gold Standard POR P16435 5447 1.6.2.4 Human 9606 Literature E 19448135 11695850 14725854 9799565 Suggested by Chandra from evidence in literature cytochrome P450 AAE Gold Standard PLA2R1 Q13018 22925 Human 9606 Mike L. Keyword search E 7721806 UniProtKB keyword search: arachidonic acid. Soluble and membrane-bound human sPLA2 receptors both bind sPLA2 with high affinities (PMID 7721806)